ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Phospholemman

Intramolecular
Cysteine 60 and cysteine 62
A redox-regulated disulphide may form within Phospholemman between cysteines 60 and 62 (40 and 42 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
49
PDB code
2jo1
Structure name
structure of the na,k-atpase regulatory protein fxyd1 in micelles
Structure deposition date
2007-02-18
Thiol separation (Å)
9
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
0
Peptide accession
O00168
Residue number A
60
Residue number B
62
Peptide name
Phospholemman

Ligandability

Cysteine 60 of Phospholemman

Cysteine 62 of Phospholemman

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