Mannan-binding lectin serine protease 2
Intramolecular
Cysteine 617 and cysteine 259
Cysteine 396 and cysteine 430
Cysteine 152 and cysteine 165
Cysteine 167 and cysteine 180
Cysteine 328 and cysteine 361
Cysteine 300 and cysteine 348
Cysteine 184 and cysteine 211
Cysteine 72 and cysteine 90
Cysteine 142 and cysteine 156
Cysteine 366 and cysteine 412
More...Cysteine 629 and cysteine 660
Cysteine 598 and cysteine 618
Cysteine 434 and cysteine 552
Cysteine 152 and cysteine 156
Cysteine 142 and cysteine 152
Cysteine 156 and cysteine 165
Cysteine 142 and cysteine 165
Cysteine 165 and cysteine 180
Cysteine 152 and cysteine 180
Cysteine 165 and cysteine 167
Cysteine 152 and cysteine 167
1nt0 G 222 G 240
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 617 and 259 (222 and 240 respectively in this structure).
Details
Redox score ?
89
PDB code
1nt0
Structure name
crystal structure of the cub1-egf-cub2 region of masp2
Structure deposition date
2003-01-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9JJS8
Residue number A
617
Residue number B
259
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 617 of Mannan-binding lectin serine protease 2
Cysteine 259 of Mannan-binding lectin serine protease 2
Uncertain whether structure cysteine 222 has been assigned to correct residue.
5jpm G 396 G 430
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 396 and 430.
Details
Redox score ?
87
PDB code
5jpm
Structure name
structure of the complex of human complement c4 with masp-2 rebuilt using imdff
Structure deposition date
2016-05-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
396
Residue number B
430
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 396 of Mannan-binding lectin serine protease 2
Cysteine 430 of Mannan-binding lectin serine protease 2
1szb A 137 A 150
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 152 and 165 (137 and 150 respectively in this structure).
Details
Redox score ?
87
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
152
Residue number B
165
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 152 of Mannan-binding lectin serine protease 2
Cysteine 165 of Mannan-binding lectin serine protease 2
1szb A 152 A 165
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 167 and 180 (152 and 165 respectively in this structure).
Details
Redox score ?
86
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
167
Residue number B
180
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 167 of Mannan-binding lectin serine protease 2
Cysteine 180 of Mannan-binding lectin serine protease 2
5jpm I 328 I 361
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 328 and 361.
Details
Redox score ?
86
PDB code
5jpm
Structure name
structure of the complex of human complement c4 with masp-2 rebuilt using imdff
Structure deposition date
2016-05-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
60
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
328
Residue number B
361
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 328 of Mannan-binding lectin serine protease 2
Cysteine 361 of Mannan-binding lectin serine protease 2
5jpm G 300 G 348
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 300 and 348.
Details
Redox score ?
86
PDB code
5jpm
Structure name
structure of the complex of human complement c4 with masp-2 rebuilt using imdff
Structure deposition date
2016-05-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
300
Residue number B
348
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 300 of Mannan-binding lectin serine protease 2
Cysteine 348 of Mannan-binding lectin serine protease 2
1nt0 G 165 G 192
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 184 and 211 (165 and 192 respectively in this structure).
Details
Redox score ?
86
PDB code
1nt0
Structure name
crystal structure of the cub1-egf-cub2 region of masp2
Structure deposition date
2003-01-28
Thiol separation (Å)
2
Half-sphere exposure sum ?
62
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9JJS8
Residue number A
184
Residue number B
211
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 184 of Mannan-binding lectin serine protease 2
Cysteine 211 of Mannan-binding lectin serine protease 2
1szb B 57 B 75
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 72 and 90 (57 and 75 respectively in this structure).
Details
Redox score ?
85
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
67
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
72
Residue number B
90
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 72 of Mannan-binding lectin serine protease 2
Cysteine 90 of Mannan-binding lectin serine protease 2
1szb B 127 B 141
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 142 and 156 (127 and 141 respectively in this structure).
Details
Redox score ?
84
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
142
Residue number B
156
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 142 of Mannan-binding lectin serine protease 2
Cysteine 156 of Mannan-binding lectin serine protease 2
5jpm G 366 G 412
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 366 and 412.
Details
Redox score ?
81
PDB code
5jpm
Structure name
structure of the complex of human complement c4 with masp-2 rebuilt using imdff
Structure deposition date
2016-05-03
Thiol separation (Å)
2
Half-sphere exposure sum ?
77
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
366
Residue number B
412
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 366 of Mannan-binding lectin serine protease 2
Cysteine 412 of Mannan-binding lectin serine protease 2
1q3x A 629 A 660
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 629 and 660.
Details
Redox score ?
80
PDB code
1q3x
Structure name
crystal structure of the catalytic region of human masp-2
Structure deposition date
2003-08-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
629
Residue number B
660
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 629 of Mannan-binding lectin serine protease 2
Cysteine 660 of Mannan-binding lectin serine protease 2
1q3x B 598 B 618
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 598 and 618.
Details
Redox score ?
79
PDB code
1q3x
Structure name
crystal structure of the catalytic region of human masp-2
Structure deposition date
2003-08-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
83
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
598
Residue number B
618
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 598 of Mannan-binding lectin serine protease 2
Cysteine 618 of Mannan-binding lectin serine protease 2
1q3x B 434 B 552
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 434 and 552.
Details
Redox score ?
78
PDB code
1q3x
Structure name
crystal structure of the catalytic region of human masp-2
Structure deposition date
2003-08-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
434
Residue number B
552
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 434 of Mannan-binding lectin serine protease 2
Cysteine 552 of Mannan-binding lectin serine protease 2
1szb A 137 A 141
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 152 and 156 (137 and 141 respectively in this structure).
Details
Redox score ?
77
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
4
Half-sphere exposure sum ?
57
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
152
Residue number B
156
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 152 of Mannan-binding lectin serine protease 2
Cysteine 156 of Mannan-binding lectin serine protease 2
1szb A 127 A 137
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 142 and 152 (127 and 137 respectively in this structure).
Details
Redox score ?
68
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
6
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
142
Residue number B
152
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 142 of Mannan-binding lectin serine protease 2
Cysteine 152 of Mannan-binding lectin serine protease 2
1szb B 141 B 150
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 156 and 165 (141 and 150 respectively in this structure).
Details
Redox score ?
65
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
61
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
156
Residue number B
165
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 156 of Mannan-binding lectin serine protease 2
Cysteine 165 of Mannan-binding lectin serine protease 2
1szb B 127 B 150
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 142 and 165 (127 and 150 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
57
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
7
Half-sphere exposure sum ?
55
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
142
Residue number B
165
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 142 of Mannan-binding lectin serine protease 2
Cysteine 165 of Mannan-binding lectin serine protease 2
1szb A 150 A 165
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 165 and 180 (150 and 165 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
7
Half-sphere exposure sum ?
52
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
165
Residue number B
180
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 165 of Mannan-binding lectin serine protease 2
Cysteine 180 of Mannan-binding lectin serine protease 2
1szb A 137 A 165
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 152 and 180 (137 and 165 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
54
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
50
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
152
Residue number B
180
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 152 of Mannan-binding lectin serine protease 2
Cysteine 180 of Mannan-binding lectin serine protease 2
1szb B 150 B 152
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 165 and 167 (150 and 152 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
8
Half-sphere exposure sum ?
56
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
165
Residue number B
167
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 165 of Mannan-binding lectin serine protease 2
Cysteine 167 of Mannan-binding lectin serine protease 2
1szb A 137 A 152
A redox-regulated disulphide may form within Mannan-binding lectin serine protease 2 between cysteines 152 and 167 (137 and 152 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
1szb
Structure name
crystal structure of the human mbl-associated protein 19 (map19)
Structure deposition date
2004-04-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
54
Minimum pKa ?
nan
% buried
nan
Peptide accession
O00187
Residue number A
152
Residue number B
167
Peptide name
Mannan-binding lectin serine protease 2
Ligandability
Cysteine 152 of Mannan-binding lectin serine protease 2
Cysteine 167 of Mannan-binding lectin serine protease 2
If this tool was useful for finding a disulphide, please cite: