Amyloid beta precursor protein binding family B member 1
Intermolecular
Cysteine 661 and cysteine 661
Intramolecular
Cysteine 397 and cysteine 479
Cysteine 604 and cysteine 633
Cysteine 633 and cysteine 634
5nqh A 661 D 661
A redox-regulated disulphide may form between two units of Amyloid beta precursor protein binding family B member 1 at cysteines 661 and 661.
Details
Redox score ?
81
PDB code
5nqh
Structure name
structure of the human fe65-ptb2 homodimer
Structure deposition date
2017-04-20
Thiol separation (Å)
2
Half-sphere exposure sum ?
90
Minimum pKa ?
nan
% buried
nan
Peptide A name
Amyloid beta precursor protein binding family B member 1
Peptide B name
Amyloid beta precursor protein binding family B member 1
Peptide A accession
O00213
Peptide B accession
O00213
Peptide A residue number
661
Peptide B residue number
661
Ligandability
3d8e C 397 C 479
A redox-regulated disulphide may form within Amyloid beta precursor protein binding family B member 1 between cysteines 397 and 479.
Details
Redox score ?
71
PDB code
3d8e
Structure name
crystal structure of the human fe65-ptb1 domain (trigonal crystal form)
Structure deposition date
2008-05-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
84
Minimum pKa ?
8
% buried
88
Peptide accession
O00213
Residue number A
397
Residue number B
479
Peptide name
Amyloid beta precursor protein binding family B member 1
Ligandability
Cysteine 397 of Amyloid beta precursor protein binding family B member 1
Cysteine 479 of Amyloid beta precursor protein binding family B member 1
5nqh D 604 D 633
A redox-regulated disulphide may form within Amyloid beta precursor protein binding family B member 1 between cysteines 604 and 633. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
5nqh
Structure name
structure of the human fe65-ptb2 homodimer
Structure deposition date
2017-04-20
Thiol separation (Å)
7
Half-sphere exposure sum ?
62
Minimum pKa ?
10
% buried
51
Peptide accession
O00213
Residue number A
604
Residue number B
633
Peptide name
Amyloid beta precursor protein binding family B member 1
Ligandability
Cysteine 604 of Amyloid beta precursor protein binding family B member 1
Cysteine 633 of Amyloid beta precursor protein binding family B member 1
5nqh D 633 D 634
A redox-regulated disulphide may form within Amyloid beta precursor protein binding family B member 1 between cysteines 633 and 634. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
5nqh
Structure name
structure of the human fe65-ptb2 homodimer
Structure deposition date
2017-04-20
Thiol separation (Å)
7
Half-sphere exposure sum ?
74
Minimum pKa ?
10
% buried
54
Peptide accession
O00213
Residue number A
633
Residue number B
634
Peptide name
Amyloid beta precursor protein binding family B member 1
Ligandability
Cysteine 633 of Amyloid beta precursor protein binding family B member 1
Cysteine 634 of Amyloid beta precursor protein binding family B member 1
If this tool was useful for finding a disulphide, please cite: