ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

26S proteasome non-ATPase regulatory subunit 11

Intramolecular
Cysteine 110 and cysteine 113
A redox-regulated disulphide may form within 26S proteasome non-ATPase regulatory subunit 11 between cysteines 110 and 113. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
6epc
Structure name
ground state 26s proteasome (gs2)
Structure deposition date
2017-10-11
Thiol separation (Å)
6
Half-sphere exposure sum ?
75
Minimum pKa ?
12
% buried
96
Peptide accession
F1LMZ8
Residue number A
110
Residue number B
113
Peptide name
26S proteasome non-ATPase regulatory subunit 11

Ligandability

Cysteine 110 of 26S proteasome non-ATPase regulatory subunit 11

Cysteine 113 of 26S proteasome non-ATPase regulatory subunit 11

If this tool was useful for finding a disulphide, please cite: