a tool for identifying drug-targetable redox-active disulphides

Chloride intracellular channel protein 1

Intramolecular

Cysteine 24 and cysteine 59 L

A redox-regulated disulphide may form within Chloride intracellular channel protein 1 between cysteines 24 and 59.

Details

Redox score ?

85

PDB code

Structure name

crystal structure of a soluble dimeric form of oxidised clic1

Structure deposition date

2003-11-20

Thiol separation (Å)

2

Half-sphere exposure sum ?

53

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

24

Residue number B

59

Peptide name

Chloride intracellular channel protein 1

Ligandability

Cysteine 24 of Chloride intracellular channel protein 1

Ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

Cysteine 59 of Chloride intracellular channel protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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