LINE-1 retrotransposable element ORF2 protein

Intramolecular

A redox-regulated disulphide may form within LINE-1 retrotransposable element ORF2 protein between cysteines 39 and 40. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7n8s

Structure name

line-1 endonuclease domain complex with dna

Structure deposition date

2021-06-15

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

O00370

Residue number A

Residue number B

Peptide name

LINE-1 retrotransposable element ORF2 protein

Ligandability

Cysteine 39 of LINE-1 retrotransposable element ORF2 protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.