Butyrophilin subfamily 3 member A3

Intramolecular

A redox-regulated disulphide may form within Butyrophilin subfamily 3 member A3 between cysteines 52 and 126 (23 and 97 respectively in this structure).

Details

Redox score ?

PDB code

4f8t

Structure name

crystal structure of the human btn3a3 ectodomain

Structure deposition date

2012-05-17

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

O00478

Residue number A

Residue number B

126

Peptide name

Butyrophilin subfamily 3 member A3

Ligandability

Cysteine 52 of Butyrophilin subfamily 3 member A3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 126 of Butyrophilin subfamily 3 member A3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Butyrophilin subfamily 3 member A3 between cysteines 166 and 220 (137 and 191 respectively in this structure).

Details

Redox score ?

PDB code

4f8t

Structure name

crystal structure of the human btn3a3 ectodomain

Structure deposition date

2012-05-17

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

O00478

Residue number A

166

Residue number B

220

Peptide name

Butyrophilin subfamily 3 member A3

Ligandability

Cysteine 166 of Butyrophilin subfamily 3 member A3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 220 of Butyrophilin subfamily 3 member A3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Butyrophilin subfamily 3 member A3 between cysteines 383 and 412 (353 and 382 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?