Lysosomal alpha-mannosidase

Intermolecular

A redox-regulated disulphide may form between two units of Lysosomal alpha-mannosidase at cysteines 56 and 360 (55 and 358 respectively in this structure).

Details

Redox score ?

PDB code

1o7d

Structure name

the structure of the bovine lysosomal a-mannosidase suggests a novel mechanism for low ph activation

Structure deposition date

2002-10-30

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide A name

Lysosomal alpha-mannosidase

Peptide B name

Lysosomal alpha-mannosidase

Peptide A accession

Q29451

Peptide B accession

Q29451

Peptide A residue number

Peptide B residue number

360

Ligandability

Cysteine 56 of Lysosomal alpha-mannosidase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 360 of Lysosomal alpha-mannosidase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form between two units of Lysosomal alpha-mannosidase at cysteines 414 and 474 (412 and 472 respectively in this structure).