SH2B adapter protein 2

Intramolecular

A redox-regulated disulphide may form within SH2B adapter protein 2 between cysteines 446 and 469. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

1rpy

Structure name

crystal structure of the dimeric sh2 domain of aps

Structure deposition date

2003-12-03

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Q9Z200

Residue number A

446

Residue number B

469

Peptide name

SH2B adapter protein 2

Ligandability

Cysteine 446 of SH2B adapter protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.