ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Coatomer subunit epsilon

Intermolecular
Cysteine 34 and cysteine 975 of Coatomer subunit alpha
A redox-regulated disulphide may form between cysteine 34 of Coatomer subunit epsilon and cysteine 975 of Coatomer subunit alpha. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
31
PDB code
3mkr
Structure name
crystal structure of yeast alpha/epsilon-cop subcomplex of the copi vesicular coat
Structure deposition date
2010-04-15
Thiol separation (Å)
10
Half-sphere exposure sum ?
69
Minimum pKa ?
11
% buried
88
Peptide A name
Coatomer subunit epsilon
Peptide B name
Coatomer subunit alpha
Peptide A accession
Q28104
Peptide B accession
Q27954
Peptide A residue number
34
Peptide B residue number
975

Ligandability

Cysteine 34 of Coatomer subunit epsilon

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 975 of Coatomer subunit alpha

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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