Na(+)/H(+) exchange regulatory cofactor NHE-RF1

Intramolecular

A redox-regulated disulphide may form within Na(+)/H(+) exchange regulatory cofactor NHE-RF1 between cysteines 15 and 16. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4pqw

Structure name

crystal structure of phospholipase c beta 3 in complex with pdz1 of nherf1

Structure deposition date

2014-03-04

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O14745

Residue number A

Residue number B

Peptide name

Na(+)/H(+) exchange regulatory cofactor NHE-RF1

Ligandability

Cysteine 15 of Na(+)/H(+) exchange regulatory cofactor NHE-RF1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.