a tool for identifying drug-targetable redox-active disulphides

Natural cytotoxicity triggering receptor 3

Intramolecular

Cysteine 39 and cysteine 108

A redox-regulated disulphide may form within Natural cytotoxicity triggering receptor 3 between cysteines 39 and 108.

Details

Redox score ?

81

PDB code

Structure name

crystal structure of nkp30 bound to its ligand b7-h6

Structure deposition date

2010-12-06

Thiol separation (Å)

2

Half-sphere exposure sum ?

79

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

39

Residue number B

108

Peptide name

Natural cytotoxicity triggering receptor 3

Ligandability

Cysteine 39 of Natural cytotoxicity triggering receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 108 of Natural cytotoxicity triggering receptor 3

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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