Phospholipase D2

Intramolecular

A redox-regulated disulphide may form within Phospholipase D2 between cysteines 674 and 839. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7svp

Structure name

structure of compound 34 bound to human phospholipase d2 catalytic domain

Structure deposition date

2021-11-19

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O14939

Residue number A

674

Residue number B

839

Peptide name

Phospholipase D2

Ligandability

Cysteine 674 of Phospholipase D2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.