ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Aurora kinase A

Intermolecular
Cysteine 290 and cysteine 290 L
A redox-regulated disulphide is known to form between two units of Aurora kinase A at cysteines 290 and 290.

Details

Redox score ?
65
PDB code
3h10
Structure name
aurora a inhibitor complex
Structure deposition date
2009-04-10
Thiol separation (Å)
5
Half-sphere exposure sum ?
41
Minimum pKa ?
10
% buried
48
Peptide A name
Aurora kinase A
Peptide B name
Aurora kinase A
Peptide A accession
O14965
Peptide B accession
O14965
Peptide A residue number
290
Peptide B residue number
290

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Ligandable in the dataset of Kuljanin et al.

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