Tripartite motif-containing protein 66
Intramolecular
Cysteine 1120 and cysteine 1123
Cysteine 1120 and cysteine 1146
Cysteine 1108 and cysteine 1111
Cysteine 1108 and cysteine 1131
Cysteine 1120 and cysteine 1149
Cysteine 1123 and cysteine 1146
Cysteine 1123 and cysteine 1149
Cysteine 1146 and cysteine 1149
Cysteine 1111 and cysteine 1131
Cysteine 1108 and cysteine 1194
More...Cysteine 1146 and cysteine 1194
Cysteine 1108 and cysteine 1193
Cysteine 1119 and cysteine 1120
Cysteine 1123 and cysteine 1194
Cysteine 1193 and cysteine 1194
Cysteine 1119 and cysteine 1123
Cysteine 1131 and cysteine 1194
Cysteine 1131 and cysteine 1193
Cysteine 1149 and cysteine 1194
6iet A 985 A 988
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1120 and 1123 (985 and 988 respectively in this structure).
Details
Redox score ?
88
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
6
% buried
13
Peptide accession
O15016
Residue number A
1120
Residue number B
1123
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1120 of Tripartite motif-containing protein 66
Cysteine 1123 of Tripartite motif-containing protein 66
6iet A 985 A 1011
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1120 and 1146 (985 and 1011 respectively in this structure).
Details
Redox score ?
86
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
6
% buried
24
Peptide accession
O15016
Residue number A
1120
Residue number B
1146
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1120 of Tripartite motif-containing protein 66
Cysteine 1146 of Tripartite motif-containing protein 66
6ieu A 973 A 976
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1108 and 1111 (973 and 976 respectively in this structure).
Details
Redox score ?
84
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
71
Minimum pKa ?
3
% buried
56
Peptide accession
O15016
Residue number A
1108
Residue number B
1111
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1108 of Tripartite motif-containing protein 66
Cysteine 1111 of Tripartite motif-containing protein 66
6iet A 973 A 996
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1108 and 1131 (973 and 996 respectively in this structure).
Details
Redox score ?
83
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
63
Minimum pKa ?
5
% buried
40
Peptide accession
O15016
Residue number A
1108
Residue number B
1131
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1108 of Tripartite motif-containing protein 66
Cysteine 1131 of Tripartite motif-containing protein 66
6ieu A 985 A 1014
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1120 and 1149 (985 and 1014 respectively in this structure).
Details
Redox score ?
82
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
54
Minimum pKa ?
6
% buried
31
Peptide accession
O15016
Residue number A
1120
Residue number B
1149
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1120 of Tripartite motif-containing protein 66
Cysteine 1149 of Tripartite motif-containing protein 66
6iet A 988 A 1011
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1123 and 1146 (988 and 1011 respectively in this structure).
Details
Redox score ?
80
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
8
% buried
27
Peptide accession
O15016
Residue number A
1123
Residue number B
1146
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1123 of Tripartite motif-containing protein 66
Cysteine 1146 of Tripartite motif-containing protein 66
6ieu A 988 A 1014
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1123 and 1149 (988 and 1014 respectively in this structure).
Details
Redox score ?
79
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
8
% buried
32
Peptide accession
O15016
Residue number A
1123
Residue number B
1149
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1123 of Tripartite motif-containing protein 66
Cysteine 1149 of Tripartite motif-containing protein 66
6ieu A 1011 A 1014
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1146 and 1149 (1011 and 1014 respectively in this structure).
Details
Redox score ?
73
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
10
% buried
42
Peptide accession
O15016
Residue number A
1146
Residue number B
1149
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1146 of Tripartite motif-containing protein 66
Cysteine 1149 of Tripartite motif-containing protein 66
6ieu A 976 A 996
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1111 and 1131 (976 and 996 respectively in this structure).
Details
Redox score ?
71
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
4
Half-sphere exposure sum ?
70
Minimum pKa ?
8
% buried
53
Peptide accession
O15016
Residue number A
1111
Residue number B
1131
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1111 of Tripartite motif-containing protein 66
Cysteine 1131 of Tripartite motif-containing protein 66
6iet A 973 A 1059
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1108 and 1194 (973 and 1059 respectively in this structure).
Details
Redox score ?
61
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
7
Half-sphere exposure sum ?
62
Minimum pKa ?
5
% buried
56
Peptide accession
O15016
Residue number A
1108
Residue number B
1194
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1108 of Tripartite motif-containing protein 66
Cysteine 1194 of Tripartite motif-containing protein 66
6iet A 1011 A 1059
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1146 and 1194 (1011 and 1059 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
53
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
7
Half-sphere exposure sum ?
70
Minimum pKa ?
10
% buried
57
Peptide accession
O15016
Residue number A
1146
Residue number B
1194
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1146 of Tripartite motif-containing protein 66
Cysteine 1194 of Tripartite motif-containing protein 66
6ieu A 973 A 1058
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1108 and 1193 (973 and 1058 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
10
Half-sphere exposure sum ?
73
Minimum pKa ?
3
% buried
86
Peptide accession
O15016
Residue number A
1108
Residue number B
1193
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1108 of Tripartite motif-containing protein 66
Cysteine 1193 of Tripartite motif-containing protein 66
6ieu A 984 A 985
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1119 and 1120 (984 and 985 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
6
% buried
36
Peptide accession
O15016
Residue number A
1119
Residue number B
1120
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1119 of Tripartite motif-containing protein 66
Cysteine 1120 of Tripartite motif-containing protein 66
6ieu A 988 A 1059
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1123 and 1194 (988 and 1059 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
8
Half-sphere exposure sum ?
55
Minimum pKa ?
8
% buried
64
Peptide accession
O15016
Residue number A
1123
Residue number B
1194
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1123 of Tripartite motif-containing protein 66
Cysteine 1194 of Tripartite motif-containing protein 66
6iet A 1058 A 1059
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1193 and 1194 (1058 and 1059 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
7
Half-sphere exposure sum ?
73
Minimum pKa ?
11
% buried
87
Peptide accession
O15016
Residue number A
1193
Residue number B
1194
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1193 of Tripartite motif-containing protein 66
Cysteine 1194 of Tripartite motif-containing protein 66
6iet A 984 A 988
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1119 and 1123 (984 and 988 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
10
Half-sphere exposure sum ?
43
Minimum pKa ?
8
% buried
8
Peptide accession
O15016
Residue number A
1119
Residue number B
1123
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1119 of Tripartite motif-containing protein 66
Cysteine 1123 of Tripartite motif-containing protein 66
6iet A 996 A 1059
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1131 and 1194 (996 and 1059 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
38
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
11
% buried
59
Peptide accession
O15016
Residue number A
1131
Residue number B
1194
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1131 of Tripartite motif-containing protein 66
Cysteine 1194 of Tripartite motif-containing protein 66
6ieu A 996 A 1058
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1131 and 1193 (996 and 1058 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
6ieu
Structure name
the structure of trim66 phd-bromo domain with unmodified h3 n terminal peptide
Structure deposition date
2018-09-17
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
12
% buried
82
Peptide accession
O15016
Residue number A
1131
Residue number B
1193
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1131 of Tripartite motif-containing protein 66
Cysteine 1193 of Tripartite motif-containing protein 66
6iet A 1014 A 1059
A redox-regulated disulphide may form within Tripartite motif-containing protein 66 between cysteines 1149 and 1194 (1014 and 1059 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
34
PDB code
6iet
Structure name
the crystal structure of trim66 phd-bromo domain
Structure deposition date
2018-09-17
Thiol separation (Å)
10
Half-sphere exposure sum ?
56
Minimum pKa ?
11
% buried
42
Peptide accession
O15016
Residue number A
1149
Residue number B
1194
Peptide name
Tripartite motif-containing protein 66
Ligandability
Cysteine 1149 of Tripartite motif-containing protein 66
Cysteine 1194 of Tripartite motif-containing protein 66
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