a tool for identifying drug-targetable redox-active disulphides

FYN-binding protein 1

Intramolecular

Cysteine 519 and cysteine 520

A redox-regulated disulphide may form within FYN-binding protein 1 between cysteines 519 and 520 (34 and 35 respectively in this structure).

Details

Redox score ?

63

PDB code

Structure name

reduced form of adap hsh3-n-domain

Structure deposition date

2006-04-28

Thiol separation (Å)

6

Half-sphere exposure sum ?

47

Minimum pK_a ?

9

% buried

0

Peptide accession

Residue number A

519

Residue number B

520

Peptide name

FYN-binding protein 1

Ligandability

Cysteine 519 of FYN-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 520 of FYN-binding protein 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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