Protein Mdm4
Intramolecular
Cysteine 306 and cysteine 320
Cysteine 306 and cysteine 323
Cysteine 306 and cysteine 309
Cysteine 437 and cysteine 440
Cysteine 309 and cysteine 320
Cysteine 320 and cysteine 323
Cysteine 437 and cysteine 460
Cysteine 437 and cysteine 463
Cysteine 440 and cysteine 460
Cysteine 460 and cysteine 463
More...Cysteine 474 and cysteine 477
Cysteine 309 and cysteine 323
Cysteine 440 and cysteine 463
2cr8 A 14 A 28
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 306 and 320 (14 and 28 respectively in this structure).
Details
Redox score ?
93
PDB code
2cr8
Structure name
solution structure of the zf-ranbp domain of p53-binding protein mdm4
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
49
Minimum pKa ?
5
% buried
0
Peptide accession
O15151
Residue number A
306
Residue number B
320
Peptide name
Protein Mdm4
Ligandability
Cysteine 306 of Protein Mdm4
Cysteine 320 of Protein Mdm4
2cr8 A 14 A 31
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 306 and 323 (14 and 31 respectively in this structure).
Details
Redox score ?
91
PDB code
2cr8
Structure name
solution structure of the zf-ranbp domain of p53-binding protein mdm4
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
5
% buried
0
Peptide accession
O15151
Residue number A
306
Residue number B
323
Peptide name
Protein Mdm4
Ligandability
Cysteine 306 of Protein Mdm4
Cysteine 323 of Protein Mdm4
2cr8 A 14 A 17
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 306 and 309 (14 and 17 respectively in this structure).
Details
Redox score ?
89
PDB code
2cr8
Structure name
solution structure of the zf-ranbp domain of p53-binding protein mdm4
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
5
% buried
0
Peptide accession
O15151
Residue number A
306
Residue number B
309
Peptide name
Protein Mdm4
Ligandability
Cysteine 306 of Protein Mdm4
Cysteine 309 of Protein Mdm4
5mnj H 437 H 440
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 437 and 440.
Details
Redox score ?
87
PDB code
5mnj
Structure name
structure of mdm2-mdmx-ubch5b-ubiquitin complex
Structure deposition date
2016-12-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
44
Minimum pKa ?
5
% buried
10
Peptide accession
O15151
Residue number A
437
Residue number B
440
Peptide name
Protein Mdm4
Ligandability
Cysteine 437 of Protein Mdm4
Cysteine 440 of Protein Mdm4
2cr8 A 17 A 28
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 309 and 320 (17 and 28 respectively in this structure).
Details
Redox score ?
86
PDB code
2cr8
Structure name
solution structure of the zf-ranbp domain of p53-binding protein mdm4
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
7
% buried
0
Peptide accession
O15151
Residue number A
309
Residue number B
320
Peptide name
Protein Mdm4
Ligandability
Cysteine 309 of Protein Mdm4
Cysteine 320 of Protein Mdm4
2cr8 A 28 A 31
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 320 and 323 (28 and 31 respectively in this structure).
Details
Redox score ?
85
PDB code
2cr8
Structure name
solution structure of the zf-ranbp domain of p53-binding protein mdm4
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
7
% buried
0
Peptide accession
O15151
Residue number A
320
Residue number B
323
Peptide name
Protein Mdm4
Ligandability
Cysteine 320 of Protein Mdm4
Cysteine 323 of Protein Mdm4
5mnj H 437 H 460
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 437 and 460.
Details
Redox score ?
84
PDB code
5mnj
Structure name
structure of mdm2-mdmx-ubch5b-ubiquitin complex
Structure deposition date
2016-12-13
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
5
% buried
20
Peptide accession
O15151
Residue number A
437
Residue number B
460
Peptide name
Protein Mdm4
Ligandability
Cysteine 437 of Protein Mdm4
Cysteine 460 of Protein Mdm4
2vje D 437 D 463
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 437 and 463.
Details
Redox score ?
82
PDB code
2vje
Structure name
crystal structure of the mdm2-mdmx ring domain heterodimer
Structure deposition date
2007-12-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
5
% buried
18
Peptide accession
O15151
Residue number A
437
Residue number B
463
Peptide name
Protein Mdm4
Ligandability
Cysteine 437 of Protein Mdm4
Cysteine 463 of Protein Mdm4
2vjf B 440 B 460
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 440 and 460.
Details
Redox score ?
82
PDB code
2vjf
Structure name
crystal structure of the mdm2-mdmx ring domain heterodimer
Structure deposition date
2007-12-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
55
Minimum pKa ?
6
% buried
13
Peptide accession
O15151
Residue number A
440
Residue number B
460
Peptide name
Protein Mdm4
Ligandability
Cysteine 440 of Protein Mdm4
Cysteine 460 of Protein Mdm4
5mnj H 460 H 463
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 460 and 463.
Details
Redox score ?
80
PDB code
5mnj
Structure name
structure of mdm2-mdmx-ubch5b-ubiquitin complex
Structure deposition date
2016-12-13
Thiol separation (Å)
3
Half-sphere exposure sum ?
66
Minimum pKa ?
7
% buried
12
Peptide accession
O15151
Residue number A
460
Residue number B
463
Peptide name
Protein Mdm4
Ligandability
Cysteine 460 of Protein Mdm4
Cysteine 463 of Protein Mdm4
2vje D 474 D 477
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 474 and 477.
Details
Redox score ?
79
PDB code
2vje
Structure name
crystal structure of the mdm2-mdmx ring domain heterodimer
Structure deposition date
2007-12-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
53
Minimum pKa ?
8
% buried
28
Peptide accession
O15151
Residue number A
474
Residue number B
477
Peptide name
Protein Mdm4
Ligandability
Cysteine 474 of Protein Mdm4
Cysteine 477 of Protein Mdm4
2cr8 A 17 A 31
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 309 and 323 (17 and 31 respectively in this structure).
Details
Redox score ?
78
PDB code
2cr8
Structure name
solution structure of the zf-ranbp domain of p53-binding protein mdm4
Structure deposition date
2005-05-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
33
Minimum pKa ?
10
% buried
0
Peptide accession
O15151
Residue number A
309
Residue number B
323
Peptide name
Protein Mdm4
Ligandability
Cysteine 309 of Protein Mdm4
Cysteine 323 of Protein Mdm4
2vjf D 440 D 463
A redox-regulated disulphide may form within Protein Mdm4 between cysteines 440 and 463.
Details
Redox score ?
77
PDB code
2vjf
Structure name
crystal structure of the mdm2-mdmx ring domain heterodimer
Structure deposition date
2007-12-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
52
Minimum pKa ?
7
% buried
8
Peptide accession
O15151
Residue number A
440
Residue number B
463
Peptide name
Protein Mdm4
Ligandability
Cysteine 440 of Protein Mdm4
Cysteine 463 of Protein Mdm4
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