ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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CTD small phosphatase-like protein

Intramolecular
Cysteine 108 and cysteine 164
A redox-regulated disulphide may form within CTD small phosphatase-like protein between cysteines 108 and 164 (30 and 86 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
45
PDB code
2hhl
Structure name
crystal structure of the human small ctd phosphatase 3 isoform 1
Structure deposition date
2006-06-28
Thiol separation (Å)
8
Half-sphere exposure sum ?
76
Minimum pKa ?
nan
% buried
nan
Peptide accession
O15194
Residue number A
108
Residue number B
164
Peptide name
CTD small phosphatase-like protein

Ligandability

Cysteine 108 of CTD small phosphatase-like protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 164 of CTD small phosphatase-like protein

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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