28S ribosomal protein S12, mitochondrial
Intramolecular
Cysteine 81 and cysteine 93
Cysteine 80 and cysteine 81
Cysteine 81 and cysteine 132 L
Cysteine 64 and cysteine 81 L
Cysteine 93 and cysteine 132 L
Cysteine 80 and cysteine 93
8csu J 81 J 93
A redox-regulated disulphide may form within 28S ribosomal protein S12, mitochondrial between cysteines 81 and 93. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
56
PDB code
8csu
Structure name
human mitochondrial small subunit assembly intermediate (state c*)
Structure deposition date
2022-05-13
Thiol separation (Å)
5
Half-sphere exposure sum ?
82
Minimum pKa ?
12
% buried
90
Peptide accession
O15235
Residue number A
81
Residue number B
93
Peptide name
28S ribosomal protein S12, mitochondrial
Ligandability
Cysteine 81 of 28S ribosomal protein S12, mitochondrial
Cysteine 93 of 28S ribosomal protein S12, mitochondrial
8csq J 80 J 81
A redox-regulated disulphide may form within 28S ribosomal protein S12, mitochondrial between cysteines 80 and 81. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
52
PDB code
8csq
Structure name
human mitochondrial small subunit assembly intermediate (state b)
Structure deposition date
2022-05-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
74
Minimum pKa ?
8
% buried
80
Peptide accession
O15235
Residue number A
80
Residue number B
81
Peptide name
28S ribosomal protein S12, mitochondrial
Ligandability
Cysteine 80 of 28S ribosomal protein S12, mitochondrial
Cysteine 81 of 28S ribosomal protein S12, mitochondrial
8css J 81 J 132
A redox-regulated disulphide may form within 28S ribosomal protein S12, mitochondrial between cysteines 81 and 132. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
8css
Structure name
human mitochondrial small subunit assembly intermediate (state d)
Structure deposition date
2022-05-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
69
Minimum pKa ?
10
% buried
68
Peptide accession
O15235
Residue number A
81
Residue number B
132
Peptide name
28S ribosomal protein S12, mitochondrial
Ligandability
Cysteine 81 of 28S ribosomal protein S12, mitochondrial
Cysteine 132 of 28S ribosomal protein S12, mitochondrial
8css J 64 J 81
A redox-regulated disulphide may form within 28S ribosomal protein S12, mitochondrial between cysteines 64 and 81. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
8css
Structure name
human mitochondrial small subunit assembly intermediate (state d)
Structure deposition date
2022-05-13
Thiol separation (Å)
8
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
47
Peptide accession
O15235
Residue number A
64
Residue number B
81
Peptide name
28S ribosomal protein S12, mitochondrial
Ligandability
Cysteine 64 of 28S ribosomal protein S12, mitochondrial
Cysteine 81 of 28S ribosomal protein S12, mitochondrial
3jd5 L 93 L 132
A redox-regulated disulphide may form within 28S ribosomal protein S12, mitochondrial between cysteines 93 and 132. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
3jd5
Structure name
cryo-em structure of the small subunit of the mammalian mitochondrial ribosome
Structure deposition date
2016-04-08
Thiol separation (Å)
9
Half-sphere exposure sum ?
71
Minimum pKa ?
10
% buried
79
Peptide accession
Q29RU1
Residue number A
93
Residue number B
132
Peptide name
28S ribosomal protein S12, mitochondrial
Ligandability
Cysteine 93 of 28S ribosomal protein S12, mitochondrial
Cysteine 132 of 28S ribosomal protein S12, mitochondrial
6neq L 80 L 93
A redox-regulated disulphide may form within 28S ribosomal protein S12, mitochondrial between cysteines 80 and 93. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6neq
Structure name
structure of human mitochondrial translation initiation factor 3 bound to the small ribosomal subunit-class-ii
Structure deposition date
2018-12-18
Thiol separation (Å)
8
Half-sphere exposure sum ?
79
Minimum pKa ?
11
% buried
84
Peptide accession
Q29RU1
Residue number A
80
Residue number B
93
Peptide name
28S ribosomal protein S12, mitochondrial
Ligandability
Cysteine 80 of 28S ribosomal protein S12, mitochondrial
Cysteine 93 of 28S ribosomal protein S12, mitochondrial
If this tool was useful for finding a disulphide, please cite: