a tool for identifying drug-targetable redox-active disulphides

Chloride intracellular channel protein 2

Intramolecular

Cysteine 30 and cysteine 33 L

A redox-regulated disulphide may form within Chloride intracellular channel protein 2 between cysteines 30 and 33.

Details

Redox score ?

79

PDB code

Structure name

structure of human clic2, crystal form a

Structure deposition date

2007-09-02

Thiol separation (Å)

2

Half-sphere exposure sum ?

74

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

30

Residue number B

33

Peptide name

Chloride intracellular channel protein 2

Ligandability

Cysteine 30 of Chloride intracellular channel protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 33 of Chloride intracellular channel protein 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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