ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Nuclear valosin-containing protein-like

Intramolecular
Cysteine 785 and cysteine 787 L
A redox-regulated disulphide may form within Nuclear valosin-containing protein-like between cysteines 785 and 787. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
54
PDB code
2x8a
Structure name
human nuclear valosin containing protein like (nvl), c- terminal aaa-atpase domain
Structure deposition date
2010-03-08
Thiol separation (Å)
8
Half-sphere exposure sum ?
50
Minimum pKa ?
9
% buried
24
Peptide accession
O15381
Residue number A
785
Residue number B
787
Peptide name
Nuclear valosin-containing protein-like

Ligandability

Cysteine 785 of Nuclear valosin-containing protein-like

Cysteine 787 of Nuclear valosin-containing protein-like

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