ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Period circadian protein homolog 1

Intramolecular
Cysteine 336 and cysteine 337
A redox-regulated disulphide may form within Period circadian protein homolog 1 between cysteines 336 and 337. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
39
PDB code
4dj2
Structure name
unwinding the differences of the mammalian period clock proteins from crystal structure to cellular function
Structure deposition date
2012-02-01
Thiol separation (Å)
8
Half-sphere exposure sum ?
77
Minimum pKa ?
11
% buried
72
Peptide accession
O35973
Residue number A
336
Residue number B
337
Peptide name
Period circadian protein homolog 1

Ligandability

Cysteine 336 of Period circadian protein homolog 1

Cysteine 337 of Period circadian protein homolog 1

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