Methylcytosine dioxygenase TET3
Intramolecular
Cysteine 69 and cysteine 72
Cysteine 57 and cysteine 60
Cysteine 57 and cysteine 89
Cysteine 69 and cysteine 84
Cysteine 69 and cysteine 75
Cysteine 57 and cysteine 63
Cysteine 63 and cysteine 89
Cysteine 72 and cysteine 75
Cysteine 60 and cysteine 89
Cysteine 60 and cysteine 63
More...Cysteine 72 and cysteine 84
Cysteine 75 and cysteine 84
5exh C 69 C 72
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 69 and 72.
Details
Redox score ?
89
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
35
Minimum pKa ?
5
% buried
6
Peptide accession
L0HN04
Residue number A
69
Residue number B
72
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 69 of Methylcytosine dioxygenase TET3
Cysteine 72 of Methylcytosine dioxygenase TET3
5exh C 57 C 60
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 57 and 60.
Details
Redox score ?
89
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
34
Minimum pKa ?
5
% buried
0
Peptide accession
L0HN04
Residue number A
57
Residue number B
60
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 57 of Methylcytosine dioxygenase TET3
Cysteine 60 of Methylcytosine dioxygenase TET3
5exh C 57 C 89
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 57 and 89.
Details
Redox score ?
89
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
5
% buried
2
Peptide accession
L0HN04
Residue number A
57
Residue number B
89
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 57 of Methylcytosine dioxygenase TET3
Cysteine 89 of Methylcytosine dioxygenase TET3
5exh C 69 C 84
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 69 and 84.
Details
Redox score ?
88
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
5
% buried
6
Peptide accession
L0HN04
Residue number A
69
Residue number B
84
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 69 of Methylcytosine dioxygenase TET3
Cysteine 84 of Methylcytosine dioxygenase TET3
5exh C 69 C 75
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 69 and 75.
Details
Redox score ?
87
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
39
Minimum pKa ?
5
% buried
2
Peptide accession
L0HN04
Residue number A
69
Residue number B
75
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 69 of Methylcytosine dioxygenase TET3
Cysteine 75 of Methylcytosine dioxygenase TET3
5exh C 57 C 63
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 57 and 63.
Details
Redox score ?
87
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
5
% buried
1
Peptide accession
L0HN04
Residue number A
57
Residue number B
63
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 57 of Methylcytosine dioxygenase TET3
Cysteine 63 of Methylcytosine dioxygenase TET3
5exh C 63 C 89
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 63 and 89.
Details
Redox score ?
85
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
47
Minimum pKa ?
7
% buried
2
Peptide accession
L0HN04
Residue number A
63
Residue number B
89
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 63 of Methylcytosine dioxygenase TET3
Cysteine 89 of Methylcytosine dioxygenase TET3
5exh C 72 C 75
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 72 and 75.
Details
Redox score ?
85
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
39
Minimum pKa ?
7
% buried
8
Peptide accession
L0HN04
Residue number A
72
Residue number B
75
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 72 of Methylcytosine dioxygenase TET3
Cysteine 75 of Methylcytosine dioxygenase TET3
5exh C 60 C 89
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 60 and 89.
Details
Redox score ?
84
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
41
Minimum pKa ?
7
% buried
2
Peptide accession
L0HN04
Residue number A
60
Residue number B
89
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 60 of Methylcytosine dioxygenase TET3
Cysteine 89 of Methylcytosine dioxygenase TET3
5exh C 60 C 63
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 60 and 63.
Details
Redox score ?
83
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
9
% buried
1
Peptide accession
L0HN04
Residue number A
60
Residue number B
63
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 60 of Methylcytosine dioxygenase TET3
Cysteine 63 of Methylcytosine dioxygenase TET3
5exh C 72 C 84
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 72 and 84.
Details
Redox score ?
83
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
7
% buried
12
Peptide accession
L0HN04
Residue number A
72
Residue number B
84
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 72 of Methylcytosine dioxygenase TET3
Cysteine 84 of Methylcytosine dioxygenase TET3
5exh C 75 C 84
A redox-regulated disulphide may form within Methylcytosine dioxygenase TET3 between cysteines 75 and 84.
Details
Redox score ?
81
PDB code
5exh
Structure name
crystal structure of mtet3-cxxc domain in complex with 5- carboxylcytosine dna at 1
Structure deposition date
2015-11-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
8
% buried
8
Peptide accession
L0HN04
Residue number A
75
Residue number B
84
Peptide name
Methylcytosine dioxygenase TET3
Ligandability
Cysteine 75 of Methylcytosine dioxygenase TET3
Cysteine 84 of Methylcytosine dioxygenase TET3
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