ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Receptor-interacting serine/threonine-protein kinase 2

Intermolecular
Cysteine 7 and cysteine 7
A redox-regulated disulphide may form between two units of Receptor-interacting serine/threonine-protein kinase 2 at cysteines 7 and 7.

Details

Redox score ?
73
PDB code
5ar2
Structure name
rip2 kinase catalytic domain (1 - 310)
Structure deposition date
2015-09-23
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
9
% buried
2
Peptide A name
Receptor-interacting serine/threonine-protein kinase 2
Peptide B name
Receptor-interacting serine/threonine-protein kinase 2
Peptide A accession
O43353
Peptide B accession
O43353
Peptide A residue number
7
Peptide B residue number
7

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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