ER membrane protein complex subunit 8

Intramolecular

A redox-regulated disulphide may form within ER membrane protein complex subunit 8 between cysteines 12 and 57. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7ado

Structure name

cryo-em structure of human er membrane protein complex in lipid nanodiscs

Structure deposition date

2020-09-15

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O43402

Residue number A

Residue number B

Peptide name

ER membrane protein complex subunit 8

Ligandability

Cysteine 12 of ER membrane protein complex subunit 8

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.