Glutamate receptor ionotropic, delta-2
Intermolecular
Cysteine 83 and cysteine 83
Cysteine 355 and cysteine 83
Intramolecular
Cysteine 756 and cysteine 811
Cysteine 298 and cysteine 310
Cysteine 99 and cysteine 131
5l2e B 83 C 83
A redox-regulated disulphide may form between two units of Glutamate receptor ionotropic, delta-2 at cysteines 83 and 83. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
5l2e
Structure name
crystal structure of rat glutamate receptor delta-2 extracellular domain
Structure deposition date
2016-08-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
81
Minimum pKa ?
nan
% buried
nan
Peptide A name
Glutamate receptor ionotropic, delta-2
Peptide B name
Glutamate receptor ionotropic, delta-2
Peptide A accession
Q63226
Peptide B accession
Q63226
Peptide A residue number
83
Peptide B residue number
83
Ligandability
5l2e B 355 C 83
A redox-regulated disulphide may form between two units of Glutamate receptor ionotropic, delta-2 at cysteines 355 and 83. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
36
PDB code
5l2e
Structure name
crystal structure of rat glutamate receptor delta-2 extracellular domain
Structure deposition date
2016-08-01
Thiol separation (Å)
10
Half-sphere exposure sum ?
78
Minimum pKa ?
nan
% buried
nan
Peptide A name
Glutamate receptor ionotropic, delta-2
Peptide B name
Glutamate receptor ionotropic, delta-2
Peptide A accession
Q63226
Peptide B accession
Q63226
Peptide A residue number
355
Peptide B residue number
83
Ligandability
Cysteine 355 of Glutamate receptor ionotropic, delta-2
Cysteine 83 of Glutamate receptor ionotropic, delta-2
2v3t A 208 A 263
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-2 between cysteines 756 and 811 (208 and 263 respectively in this structure).
Details
Redox score ?
91
PDB code
2v3t
Structure name
structure of the ligand-binding core of the ionotropic glutamate receptor-like glurdelta2 in the apo form
Structure deposition date
2007-06-22
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63226
Residue number A
756
Residue number B
811
Peptide name
Glutamate receptor ionotropic, delta-2
Ligandability
Cysteine 756 of Glutamate receptor ionotropic, delta-2
Cysteine 811 of Glutamate receptor ionotropic, delta-2
5kc8 A 298 A 310
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-2 between cysteines 298 and 310.
Details
Redox score ?
83
PDB code
5kc8
Structure name
crystal structure of the amino-terminal domain (atd) of iglur delta-2 (glud2)
Structure deposition date
2016-06-05
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
O43424
Residue number A
298
Residue number B
310
Peptide name
Glutamate receptor ionotropic, delta-2
Ligandability
Cysteine 298 of Glutamate receptor ionotropic, delta-2
Cysteine 310 of Glutamate receptor ionotropic, delta-2
5l2e C 99 C 131
A redox-regulated disulphide may form within Glutamate receptor ionotropic, delta-2 between cysteines 99 and 131.
Details
Redox score ?
82
PDB code
5l2e
Structure name
crystal structure of rat glutamate receptor delta-2 extracellular domain
Structure deposition date
2016-08-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
66
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q63226
Residue number A
99
Residue number B
131
Peptide name
Glutamate receptor ionotropic, delta-2
Ligandability
Cysteine 99 of Glutamate receptor ionotropic, delta-2
Cysteine 131 of Glutamate receptor ionotropic, delta-2
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