ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Protein CBFA2T2

Intramolecular
Cysteine 151 and cysteine 522
A redox-regulated disulphide may form within Protein CBFA2T2 between cysteines 151 and 522 (61 and 77 respectively in this structure).

Details

Redox score ?
nan
PDB code
5ecj
Structure name
crystal structure of monobody mb(s4) bound to prdm14 in complex with mtgr1
Structure deposition date
2015-10-20
Thiol separation (Å)
8
Half-sphere exposure sum ?
61
Minimum pKa ?
10
% buried
48
Peptide accession
O70374
Residue number A
151
Residue number B
522
Peptide name
Protein CBFA2T2

Ligandability

Cysteine 151 of Protein CBFA2T2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 522 of Protein CBFA2T2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Uncertain whether structure cysteine 61 has been assigned to correct residue.
Uncertain whether structure cysteine 77 has been assigned to correct residue.
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