a tool for identifying drug-targetable redox-active disulphides

Tumor necrosis factor ligand superfamily member 14

Intramolecular

Cysteine 154 and cysteine 187 L

A redox-regulated disulphide may form within Tumor necrosis factor ligand superfamily member 14 between cysteines 154 and 187.

Details

Redox score ?

84

PDB code

Structure name

crystal structure of light

Structure deposition date

2012-04-12

Thiol separation (Å)

2

Half-sphere exposure sum ?

76

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

154

Residue number B

187

Peptide name

Tumor necrosis factor ligand superfamily member 14

Ligandability

Cysteine 154 of Tumor necrosis factor ligand superfamily member 14

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 187 of Tumor necrosis factor ligand superfamily member 14

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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