2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Intramolecular

A redox-regulated disulphide may form within 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 between cysteines 26 and 117. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4p5e

Structure name

crystal structure of human dnph1 (rcl) with 6-naphthyl-purine- riboside-monophosphate

Structure deposition date

2014-03-16

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

O43598

Residue number A

Residue number B

117

Peptide name

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Ligandability

Cysteine 26 of 2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Not ligandable in the dataset of Yang et al.

Ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 117 of 2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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