Small glutamine-rich tetratricopeptide repeat-containing protein alpha

Intermolecular

Intramolecular

A redox-regulated disulphide may form between two units of Small glutamine-rich tetratricopeptide repeat-containing protein alpha at cysteines 38 and 38. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

4gof

Structure name

crystal structure of the sgta homodimerization domain with covalent modifications to both c38

Structure deposition date

2012-08-19

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide A name

Small glutamine-rich tetratricopeptide repeat-containing protein alpha

Peptide B name

Small glutamine-rich tetratricopeptide repeat-containing protein alpha

Peptide A accession

O43765

Peptide B accession

O43765

Peptide A residue number

Peptide B residue number

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Small glutamine-rich tetratricopeptide repeat-containing protein alpha between cysteines 129 and 148. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?