Glutathione S-transferase LANCL1

A redox-regulated disulphide may form within Glutathione S-transferase LANCL1 between cysteines 355 and 363. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

8d0v

Structure name

human lancl1 c264a mutant bound to gsh

Structure deposition date

2022-05-26

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O43813

Residue number A

355

Residue number B

363

Peptide name

Glutathione S-transferase LANCL1

Ligandability

Cysteine 355 of Glutathione S-transferase LANCL1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 363 of Glutathione S-transferase LANCL1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Glutathione S-transferase LANCL1 between cysteines 252 and 305. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

8d19

Structure name

human lancl1 bound to gsh

Structure deposition date

2022-05-26

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O43813

Residue number A

252

Residue number B

305

Peptide name

Glutathione S-transferase LANCL1

Ligandability

Cysteine 252 of Glutathione S-transferase LANCL1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 305 of Glutathione S-transferase LANCL1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Glutathione S-transferase LANCL1 between cysteines 108 and 322. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?