a tool for identifying drug-targetable redox-active disulphides

Protein SCO2 homolog, mitochondrial

Intramolecular

Cysteine 133 and cysteine 137

A redox-regulated disulphide may form within Protein SCO2 homolog, mitochondrial between cysteines 133 and 137.

Details

Redox score ?

82

PDB code

Structure name

solution structure of cu(i) human sco2

Structure deposition date

2007-07-11

Thiol separation (Å)

4

Half-sphere exposure sum ?

51

Minimum pK_a ?

9

% buried

36

Peptide accession

Residue number A

133

Residue number B

137

Peptide name

Protein SCO2 homolog, mitochondrial

Ligandability

Cysteine 133 of Protein SCO2 homolog, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 137 of Protein SCO2 homolog, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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