ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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TYRO protein tyrosine kinase-binding protein

Intermolecular
Cysteine 35 and cysteine 35
A redox-regulated disulphide may form between two units of TYRO protein tyrosine kinase-binding protein at cysteines 35 and 35 (1 and 1 respectively in this structure).

Details

Redox score ?
94
PDB code
2l34
Structure name
structure of the dap12 transmembrane homodimer
Structure deposition date
2010-09-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
nan
Minimum pKa ?
nan
% buried
nan
Peptide A name
TYRO protein tyrosine kinase-binding protein
Peptide B name
TYRO protein tyrosine kinase-binding protein
Peptide A accession
O43914
Peptide B accession
O43914
Peptide A residue number
35
Peptide B residue number
35

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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