ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Adhesion G protein-coupled receptor B3

Intramolecular
Cysteine 502 and cysteine 507
Cysteine 839 and cysteine 853
Cysteine 514 and cysteine 549
Cysteine 537 and cysteine 567
Cysteine 819 and cysteine 851
Cysteine 851 and cysteine 853
Cysteine 819 and cysteine 853
Cysteine 819 and cysteine 839
Cysteine 839 and cysteine 851
A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 502 and 507.

Details

Redox score ?
90
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
22
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
502
Residue number B
507
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 502 of Adhesion G protein-coupled receptor B3

Cysteine 507 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 839 and 853.

Details

Redox score ?
89
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
839
Residue number B
853
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 839 of Adhesion G protein-coupled receptor B3

Cysteine 853 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 514 and 549.

Details

Redox score ?
86
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
59
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
514
Residue number B
549
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 514 of Adhesion G protein-coupled receptor B3

Cysteine 549 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 537 and 567.

Details

Redox score ?
84
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
63
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
537
Residue number B
567
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 537 of Adhesion G protein-coupled receptor B3

Cysteine 567 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 819 and 851.

Details

Redox score ?
81
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
2
Half-sphere exposure sum ?
91
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
819
Residue number B
851
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 819 of Adhesion G protein-coupled receptor B3

Cysteine 851 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 851 and 853.

Details

Redox score ?
63
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
5
Half-sphere exposure sum ?
85
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
851
Residue number B
853
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 851 of Adhesion G protein-coupled receptor B3

Cysteine 853 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 819 and 853.

Details

Redox score ?
61
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
819
Residue number B
853
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 819 of Adhesion G protein-coupled receptor B3

Cysteine 853 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 819 and 839.

Details

Redox score ?
61
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
86
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
819
Residue number B
839
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 819 of Adhesion G protein-coupled receptor B3

Cysteine 839 of Adhesion G protein-coupled receptor B3

A redox-regulated disulphide may form within Adhesion G protein-coupled receptor B3 between cysteines 839 and 851.

Details

Redox score ?
60
PDB code
4dlo
Structure name
crystal structure of the gain and hormr domains of brain angiogenesis inhibitor 3 (bai3)
Structure deposition date
2012-02-06
Thiol separation (Å)
6
Half-sphere exposure sum ?
84
Minimum pKa ?
nan
% buried
nan
Peptide accession
O60242
Residue number A
839
Residue number B
851
Peptide name
Adhesion G protein-coupled receptor B3

Ligandability

Cysteine 839 of Adhesion G protein-coupled receptor B3

Cysteine 851 of Adhesion G protein-coupled receptor B3

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