HMG box-containing protein 1
Intramolecular
Cysteine 434 and cysteine 501
Cysteine 214 and cysteine 334
Cysteine 325 and cysteine 326
Cysteine 214 and cysteine 325
Cysteine 214 and cysteine 296
Cysteine 296 and cysteine 334
2e6o A 18 A 85
A redox-regulated disulphide may form within HMG box-containing protein 1 between cysteines 434 and 501 (18 and 85 respectively in this structure).
Details
Redox score ?
80
PDB code
2e6o
Structure name
solution structure of the hmg box domain from human hmg-box transcription factor 1
Structure deposition date
2006-12-28
Thiol separation (Å)
5
Half-sphere exposure sum ?
27
Minimum pKa ?
9
% buried
0
Peptide accession
O60381
Residue number A
434
Residue number B
501
Peptide name
HMG box-containing protein 1
Ligandability
Cysteine 434 of HMG box-containing protein 1
Cysteine 501 of HMG box-containing protein 1
3qve A 214 A 334
A redox-regulated disulphide may form within HMG box-containing protein 1 between cysteines 214 and 334. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
49
PDB code
3qve
Structure name
crystal structure of human hmg box-containing protein 1, hbp1
Structure deposition date
2011-02-25
Thiol separation (Å)
6
Half-sphere exposure sum ?
73
Minimum pKa ?
13
% buried
100
Peptide accession
O60381
Residue number A
214
Residue number B
334
Peptide name
HMG box-containing protein 1
Ligandability
Cysteine 214 of HMG box-containing protein 1
Cysteine 334 of HMG box-containing protein 1
3qve B 325 B 326
A redox-regulated disulphide may form within HMG box-containing protein 1 between cysteines 325 and 326. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
47
PDB code
3qve
Structure name
crystal structure of human hmg box-containing protein 1, hbp1
Structure deposition date
2011-02-25
Thiol separation (Å)
8
Half-sphere exposure sum ?
73
Minimum pKa ?
10
% buried
62
Peptide accession
O60381
Residue number A
325
Residue number B
326
Peptide name
HMG box-containing protein 1
Ligandability
Cysteine 325 of HMG box-containing protein 1
Cysteine 326 of HMG box-containing protein 1
1v06 A 214 A 325
A redox-regulated disulphide may form within HMG box-containing protein 1 between cysteines 214 and 325. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
1v06
Structure name
axh domain of the transcription factor hbp1 from m
Structure deposition date
2004-03-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
64
Minimum pKa ?
9
% buried
70
Peptide accession
Q8R316
Residue number A
214
Residue number B
325
Peptide name
HMG box-containing protein 1
Ligandability
Cysteine 214 of HMG box-containing protein 1
Cysteine 325 of HMG box-containing protein 1
3qve A 214 A 296
A redox-regulated disulphide may form within HMG box-containing protein 1 between cysteines 214 and 296. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
35
PDB code
3qve
Structure name
crystal structure of human hmg box-containing protein 1, hbp1
Structure deposition date
2011-02-25
Thiol separation (Å)
9
Half-sphere exposure sum ?
70
Minimum pKa ?
13
% buried
100
Peptide accession
O60381
Residue number A
214
Residue number B
296
Peptide name
HMG box-containing protein 1
Ligandability
Cysteine 214 of HMG box-containing protein 1
Cysteine 296 of HMG box-containing protein 1
1v06 A 296 A 334
A redox-regulated disulphide may form within HMG box-containing protein 1 between cysteines 296 and 334. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
29
PDB code
1v06
Structure name
axh domain of the transcription factor hbp1 from m
Structure deposition date
2004-03-24
Thiol separation (Å)
9
Half-sphere exposure sum ?
79
Minimum pKa ?
13
% buried
100
Peptide accession
Q8R316
Residue number A
296
Residue number B
334
Peptide name
HMG box-containing protein 1
Ligandability
Cysteine 296 of HMG box-containing protein 1
Cysteine 334 of HMG box-containing protein 1
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