Cystatin-8
Intermolecular
Cysteine 95 and cysteine 139
Cysteine 105 and cysteine 139
Intramolecular
Cysteine 95 and cysteine 105
Cysteine 119 and cysteine 139
6uio A 95 B 139
A redox-regulated disulphide may form between two units of Cystatin-8 at cysteines 95 and 139. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
6uio
Structure name
crystal structure of mouse cres (cystatin-related epididymal spermatogenic)
Structure deposition date
2019-10-01
Thiol separation (Å)
8
Half-sphere exposure sum ?
72
Minimum pKa ?
nan
% buried
nan
Peptide A name
Cystatin-8
Peptide B name
Cystatin-8
Peptide A accession
P32766
Peptide B accession
P32766
Peptide A residue number
95
Peptide B residue number
139
Ligandability
Cysteine 95 of Cystatin-8
Cysteine 139 of Cystatin-8
6uio A 105 B 139
A redox-regulated disulphide may form between two units of Cystatin-8 at cysteines 105 and 139. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
42
PDB code
6uio
Structure name
crystal structure of mouse cres (cystatin-related epididymal spermatogenic)
Structure deposition date
2019-10-01
Thiol separation (Å)
9
Half-sphere exposure sum ?
69
Minimum pKa ?
nan
% buried
nan
Peptide A name
Cystatin-8
Peptide B name
Cystatin-8
Peptide A accession
P32766
Peptide B accession
P32766
Peptide A residue number
105
Peptide B residue number
139
Ligandability
Cysteine 105 of Cystatin-8
Cysteine 139 of Cystatin-8
6uio C 95 C 105
A redox-regulated disulphide may form within Cystatin-8 between cysteines 95 and 105.
Details
Redox score ?
86
PDB code
6uio
Structure name
crystal structure of mouse cres (cystatin-related epididymal spermatogenic)
Structure deposition date
2019-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
58
Minimum pKa ?
nan
% buried
nan
Peptide accession
P32766
Residue number A
95
Residue number B
105
Peptide name
Cystatin-8
Ligandability
Cysteine 95 of Cystatin-8
Cysteine 105 of Cystatin-8
6uio B 119 B 139
A redox-regulated disulphide may form within Cystatin-8 between cysteines 119 and 139.
Details
Redox score ?
84
PDB code
6uio
Structure name
crystal structure of mouse cres (cystatin-related epididymal spermatogenic)
Structure deposition date
2019-10-01
Thiol separation (Å)
2
Half-sphere exposure sum ?
73
Minimum pKa ?
nan
% buried
nan
Peptide accession
P32766
Residue number A
119
Residue number B
139
Peptide name
Cystatin-8
Ligandability
Cysteine 119 of Cystatin-8
Cysteine 139 of Cystatin-8
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