6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

Intramolecular

A redox-regulated disulphide may form within 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 between cysteines 398 and 416. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

5hr5

Structure name

bovine heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (pfkfb2)

Structure deposition date

2016-01-22

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

P26285

Residue number A

398

Residue number B

416

Peptide name

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

Ligandability

Cysteine 398 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.