H/ACA ribonucleoprotein complex subunit DKC1

Intramolecular

A redox-regulated disulphide may form within H/ACA ribonucleoprotein complex subunit DKC1 between cysteines 74 and 310. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

7bgb

Structure name

the h/aca rnp lobe of human telomerase

Structure deposition date

2021-01-06

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O60832

Residue number A

Residue number B

310

Peptide name

H/ACA ribonucleoprotein complex subunit DKC1

Ligandability

Cysteine 74 of H/ACA ribonucleoprotein complex subunit DKC1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 310 of H/ACA ribonucleoprotein complex subunit DKC1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within H/ACA ribonucleoprotein complex subunit DKC1 between cysteines 310 and 344. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?