Cystinosin

Intramolecular

A redox-regulated disulphide may form within Cystinosin between cysteines 223 and 224. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

8dyp

Structure name

crystal structure of human cystine transporter cystinosin

Structure deposition date

2022-08-04

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O60931

Residue number A

223

Residue number B

224

Peptide name

Cystinosin

Ligandability

Cysteine 223 of Cystinosin

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.