ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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Zinc finger protein ZPR1

Intramolecular
Cysteine 51 and cysteine 54
Cysteine 288 and cysteine 291
Cysteine 54 and cysteine 83
Cysteine 54 and cysteine 80
Cysteine 51 and cysteine 80
Cysteine 259 and cysteine 262
Cysteine 51 and cysteine 83
Cysteine 80 and cysteine 83
Cysteine 262 and cysteine 288
Cysteine 262 and cysteine 291
More...
Cysteine 259 and cysteine 291
Cysteine 259 and cysteine 288
A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 51 and 54.

Details

Redox score ?
89
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
5
% buried
0
Peptide accession
Q62384
Residue number A
51
Residue number B
54
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 51 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 54 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 288 and 291.

Details

Redox score ?
88
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
2
Half-sphere exposure sum ?
42
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62384
Residue number A
288
Residue number B
291
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 288 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 291 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 54 and 83.

Details

Redox score ?
87
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
32
Minimum pKa ?
5
% buried
0
Peptide accession
Q62384
Residue number A
54
Residue number B
83
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 54 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 83 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 54 and 80.

Details

Redox score ?
87
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
42
Minimum pKa ?
5
% buried
0
Peptide accession
Q62384
Residue number A
54
Residue number B
80
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 54 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 80 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 51 and 80.

Details

Redox score ?
86
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
48
Minimum pKa ?
7
% buried
0
Peptide accession
Q62384
Residue number A
51
Residue number B
80
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 51 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 80 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 259 and 262.

Details

Redox score ?
86
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
2
Half-sphere exposure sum ?
46
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62384
Residue number A
259
Residue number B
262
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 259 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 262 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 51 and 83.

Details

Redox score ?
85
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
38
Minimum pKa ?
9
% buried
0
Peptide accession
Q62384
Residue number A
51
Residue number B
83
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 51 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 83 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 80 and 83.

Details

Redox score ?
85
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
40
Minimum pKa ?
7
% buried
0
Peptide accession
Q62384
Residue number A
80
Residue number B
83
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 80 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 83 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 262 and 288.

Details

Redox score ?
78
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
45
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62384
Residue number A
262
Residue number B
288
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 262 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 288 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 262 and 291.

Details

Redox score ?
77
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
3
Half-sphere exposure sum ?
37
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62384
Residue number A
262
Residue number B
291
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 262 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 291 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 259 and 291.

Details

Redox score ?
77
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
43
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62384
Residue number A
259
Residue number B
291
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 259 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 291 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Zinc finger protein ZPR1 between cysteines 259 and 288.

Details

Redox score ?
77
PDB code
2qkd
Structure name
crystal structure of tandem zpr1 domains
Structure deposition date
2007-07-10
Thiol separation (Å)
4
Half-sphere exposure sum ?
51
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q62384
Residue number A
259
Residue number B
288
Peptide name
Zinc finger protein ZPR1

Ligandability

Cysteine 259 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 288 of Zinc finger protein ZPR1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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