ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Tripartite motif-containing protein 3

Intramolecular
Cysteine 597 and cysteine 598
A redox-regulated disulphide may form within Tripartite motif-containing protein 3 between cysteines 597 and 598. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
50
PDB code
7qrw
Structure name
crystal structure of nhl domain of trim3
Structure deposition date
2022-01-12
Thiol separation (Å)
7
Half-sphere exposure sum ?
75
Minimum pKa ?
9
% buried
42
Peptide accession
O75382
Residue number A
597
Residue number B
598
Peptide name
Tripartite motif-containing protein 3

Ligandability

Cysteine 597 of Tripartite motif-containing protein 3

Cysteine 598 of Tripartite motif-containing protein 3

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