Nuclear receptor subfamily 1 group I member 2

Intramolecular

A redox-regulated disulphide may form within Nuclear receptor subfamily 1 group I member 2 between cysteines 284 and 301. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

6p2b

Structure name

tethered pxr-lbd/src-1p bound to garcinoic acid

Structure deposition date

2019-05-21

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

100

Peptide accession

O75469

Residue number A

284

Residue number B

301

Peptide name

Nuclear receptor subfamily 1 group I member 2

Ligandability

Cysteine 284 of Nuclear receptor subfamily 1 group I member 2

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.