a tool for identifying drug-targetable redox-active disulphides

Protein CREG1

Intramolecular

Cysteine 135 and cysteine 147

A redox-regulated disulphide may form within Protein CREG1 between cysteines 135 and 147 (99 and 111 respectively in this structure).

Details

Redox score ?

86

PDB code

Structure name

the crystal structure of cellular repressor of e1a- stimulated genes (creg)

Structure deposition date

2004-09-20

Thiol separation (Å)

2

Half-sphere exposure sum ?

60

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

135

Residue number B

147

Peptide name

Protein CREG1

Ligandability

Cysteine 135 of Protein CREG1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 147 of Protein CREG1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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