WD repeat and HMG-box DNA-binding protein 1
Intermolecular
Cysteine 598 and cysteine 598
Intramolecular
Cysteine 31 and cysteine 60
Cysteine 156 and cysteine 180 L
Cysteine 773 and cysteine 781 L
Cysteine 20 and cysteine 60
Cysteine 241 and cysteine 304
Cysteine 668 and cysteine 689
Cysteine 668 and cysteine 692
Cysteine 662 and cysteine 689
Cysteine 264 and cysteine 304
More...Cysteine 662 and cysteine 668
Cysteine 689 and cysteine 692
Cysteine 20 and cysteine 31
Cysteine 31 and cysteine 277
6xty G 598 H 598
A redox-regulated disulphide may form between two units of WD repeat and HMG-box DNA-binding protein 1 at cysteines 598 and 598. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
6xty
Structure name
cryoem structure of human cmg bound to and-1 (cmga)
Structure deposition date
2020-01-16
Thiol separation (Å)
8
Half-sphere exposure sum ?
88
Minimum pKa ?
9
% buried
100
Peptide A name
WD repeat and HMG-box DNA-binding protein 1
Peptide B name
WD repeat and HMG-box DNA-binding protein 1
Peptide A accession
O75717
Peptide B accession
O75717
Peptide A residue number
598
Peptide B residue number
598
Ligandability
5gva A 31 A 60
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 31 and 60.
Details
Redox score ?
77
PDB code
5gva
Structure name
wd40 domain of human and-1
Structure deposition date
2016-09-04
Thiol separation (Å)
2
Half-sphere exposure sum ?
99
Minimum pKa ?
nan
% buried
nan
Peptide accession
O75717
Residue number A
31
Residue number B
60
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 31 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 60 of WD repeat and HMG-box DNA-binding protein 1
5gva A 156 A 180
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 156 and 180.
Details
Redox score ?
74
PDB code
5gva
Structure name
wd40 domain of human and-1
Structure deposition date
2016-09-04
Thiol separation (Å)
4
Half-sphere exposure sum ?
59
Minimum pKa ?
9
% buried
34
Peptide accession
O75717
Residue number A
156
Residue number B
180
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 156 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 180 of WD repeat and HMG-box DNA-binding protein 1
5gvb A 773 A 781
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 773 and 781.
Details
Redox score ?
72
PDB code
5gvb
Structure name
sepb domain of human and-1
Structure deposition date
2016-09-05
Thiol separation (Å)
5
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
34
Peptide accession
O75717
Residue number A
773
Residue number B
781
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 773 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 781 of WD repeat and HMG-box DNA-binding protein 1
5gva A 20 A 60
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 20 and 60. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
51
PDB code
5gva
Structure name
wd40 domain of human and-1
Structure deposition date
2016-09-04
Thiol separation (Å)
6
Half-sphere exposure sum ?
89
Minimum pKa ?
12
% buried
nan
Peptide accession
O75717
Residue number A
20
Residue number B
60
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 20 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 60 of WD repeat and HMG-box DNA-binding protein 1
5gva A 241 A 304
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 241 and 304. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
50
PDB code
5gva
Structure name
wd40 domain of human and-1
Structure deposition date
2016-09-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
50
Minimum pKa ?
8
% buried
34
Peptide accession
O75717
Residue number A
241
Residue number B
304
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 241 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 304 of WD repeat and HMG-box DNA-binding protein 1
5gvb A 668 A 689
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 668 and 689. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
48
PDB code
5gvb
Structure name
sepb domain of human and-1
Structure deposition date
2016-09-05
Thiol separation (Å)
9
Half-sphere exposure sum ?
57
Minimum pKa ?
10
% buried
48
Peptide accession
O75717
Residue number A
668
Residue number B
689
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 668 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 689 of WD repeat and HMG-box DNA-binding protein 1
5ogs A 668 A 692
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 668 and 692. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
46
PDB code
5ogs
Structure name
crystal structure of human and-1 sepb domain
Structure deposition date
2017-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
49
Minimum pKa ?
10
% buried
42
Peptide accession
O75717
Residue number A
668
Residue number B
692
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 668 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 692 of WD repeat and HMG-box DNA-binding protein 1
5ogs A 662 A 689
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 662 and 689. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
45
PDB code
5ogs
Structure name
crystal structure of human and-1 sepb domain
Structure deposition date
2017-07-13
Thiol separation (Å)
7
Half-sphere exposure sum ?
68
Minimum pKa ?
12
% buried
83
Peptide accession
O75717
Residue number A
662
Residue number B
689
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 662 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 689 of WD repeat and HMG-box DNA-binding protein 1
5gva A 264 A 304
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 264 and 304. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
41
PDB code
5gva
Structure name
wd40 domain of human and-1
Structure deposition date
2016-09-04
Thiol separation (Å)
9
Half-sphere exposure sum ?
55
Minimum pKa ?
10
% buried
42
Peptide accession
O75717
Residue number A
264
Residue number B
304
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 264 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 304 of WD repeat and HMG-box DNA-binding protein 1
5ogs A 662 A 668
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 662 and 668. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
5ogs
Structure name
crystal structure of human and-1 sepb domain
Structure deposition date
2017-07-13
Thiol separation (Å)
10
Half-sphere exposure sum ?
56
Minimum pKa ?
10
% buried
53
Peptide accession
O75717
Residue number A
662
Residue number B
668
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 662 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 668 of WD repeat and HMG-box DNA-binding protein 1
5ogs A 689 A 692
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 689 and 692. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
40
PDB code
5ogs
Structure name
crystal structure of human and-1 sepb domain
Structure deposition date
2017-07-13
Thiol separation (Å)
9
Half-sphere exposure sum ?
60
Minimum pKa ?
12
% buried
72
Peptide accession
O75717
Residue number A
689
Residue number B
692
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 689 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 692 of WD repeat and HMG-box DNA-binding protein 1
5gva A 20 A 31
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 20 and 31. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
37
PDB code
5gva
Structure name
wd40 domain of human and-1
Structure deposition date
2016-09-04
Thiol separation (Å)
8
Half-sphere exposure sum ?
92
Minimum pKa ?
12
% buried
nan
Peptide accession
O75717
Residue number A
20
Residue number B
31
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 20 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 31 of WD repeat and HMG-box DNA-binding protein 1
5gva A 31 A 277
A redox-regulated disulphide may form within WD repeat and HMG-box DNA-binding protein 1 between cysteines 31 and 277. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?
Details
Redox score ?
24
PDB code
5gva
Structure name
wd40 domain of human and-1
Structure deposition date
2016-09-04
Thiol separation (Å)
10
Half-sphere exposure sum ?
100
Minimum pKa ?
12
% buried
nan
Peptide accession
O75717
Residue number A
31
Residue number B
277
Peptide name
WD repeat and HMG-box DNA-binding protein 1
Ligandability
Cysteine 31 of WD repeat and HMG-box DNA-binding protein 1
Cysteine 277 of WD repeat and HMG-box DNA-binding protein 1
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