ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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26S proteasome non-ATPase regulatory subunit 10

Intramolecular
Cysteine 4 and cysteine 11
A redox-regulated disulphide may form within 26S proteasome non-ATPase regulatory subunit 10 between cysteines 4 and 11.

Details

Redox score ?
60
PDB code
4nik
Structure name
structure of human gankyrin in complex to the single chain antibody f5
Structure deposition date
2013-11-06
Thiol separation (Å)
7
Half-sphere exposure sum ?
64
Minimum pKa ?
10
% buried
40
Peptide accession
O75832
Residue number A
4
Residue number B
11
Peptide name
26S proteasome non-ATPase regulatory subunit 10

Ligandability

Cysteine 4 of 26S proteasome non-ATPase regulatory subunit 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 11 of 26S proteasome non-ATPase regulatory subunit 10

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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