a tool for identifying drug-targetable redox-active disulphides

Protein SCO1 homolog, mitochondrial

Intramolecular

Cysteine 169 and cysteine 173

A redox-regulated disulphide may form within Protein SCO1 homolog, mitochondrial between cysteines 169 and 173.

Details

Redox score ?

74

PDB code

Structure name

human sco1

Structure deposition date

2004-08-27

Thiol separation (Å)

5

Half-sphere exposure sum ?

59

Minimum pK_a ?

7

% buried

76

Peptide accession

Residue number A

169

Residue number B

173

Peptide name

Protein SCO1 homolog, mitochondrial

Ligandability

Cysteine 169 of Protein SCO1 homolog, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 173 of Protein SCO1 homolog, mitochondrial

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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