ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Home
About
List

Cytosolic 10-formyltetrahydrofolate dehydrogenase

Intramolecular
Cysteine 567 and cysteine 587
A redox-regulated disulphide may form within Cytosolic 10-formyltetrahydrofolate dehydrogenase between cysteines 567 and 587.

Details

Redox score ?
65
PDB code
3rhm
Structure name
crystal structure of the e673q mutant of c-terminal domain of 10'formyltetrahydrofolate dehydrogenase
Structure deposition date
2011-04-11
Thiol separation (Å)
4
Half-sphere exposure sum ?
100
Minimum pKa ?
8
% buried
100
Peptide accession
Q5HZB2
Residue number A
567
Residue number B
587
Peptide name
Cytosolic 10-formyltetrahydrofolate dehydrogenase

Ligandability

Cysteine 567 of Cytosolic 10-formyltetrahydrofolate dehydrogenase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 587 of Cytosolic 10-formyltetrahydrofolate dehydrogenase

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: