Natural cytotoxicity triggering receptor 1

Intramolecular

A redox-regulated disulphide may form within Natural cytotoxicity triggering receptor 1 between cysteines 49 and 98 (25 and 74 respectively in this structure).

Details

Redox score ?

PDB code

1oll

Structure name

extracellular region of the human receptor nkp46

Structure deposition date

2003-08-07

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

O76016

Residue number A

Residue number B

Peptide name

Natural cytotoxicity triggering receptor 1

Ligandability

Cysteine 49 of Natural cytotoxicity triggering receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 98 of Natural cytotoxicity triggering receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Natural cytotoxicity triggering receptor 1 between cysteines 144 and 190 (120 and 166 respectively in this structure).

Details

Redox score ?

PDB code

1oll

Structure name

extracellular region of the human receptor nkp46

Structure deposition date

2003-08-07

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

nan

% buried

nan

Peptide accession

O76016

Residue number A

144

Residue number B

190

Peptide name

Natural cytotoxicity triggering receptor 1

Ligandability

Cysteine 144 of Natural cytotoxicity triggering receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 190 of Natural cytotoxicity triggering receptor 1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within Natural cytotoxicity triggering receptor 1 between cysteines 48 and 49 (24 and 25 respectively in this structure). However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?