Bestrophin-1

Intramolecular

A redox-regulated disulphide may form within Bestrophin-1 between cysteines 69 and 251. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?

PDB code

8d1j

Structure name

hbest1 5mm ca2+ (ca2+-bound) closed state

Structure deposition date

2022-05-27

Thiol separation (Å)

Half-sphere exposure sum ?

Minimum pK_a ?

% buried

Peptide accession

O76090

Residue number A

Residue number B

251

Peptide name

Bestrophin-1

Ligandability

Cysteine 69 of Bestrophin-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.