a tool for identifying drug-targetable redox-active disulphides

Fibroblast growth factor 18

Intramolecular

Cysteine 109 and cysteine 127

A redox-regulated disulphide may form within Fibroblast growth factor 18 between cysteines 109 and 127.

Details

Redox score ?

78

PDB code

Structure name

crystal structure of human fgf18

Structure deposition date

2013-12-21

Thiol separation (Å)

2

Half-sphere exposure sum ?

82

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

109

Residue number B

127

Peptide name

Fibroblast growth factor 18

Ligandability

Cysteine 109 of Fibroblast growth factor 18

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 127 of Fibroblast growth factor 18

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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